منابع مشابه
Two-period, two-treatment crossover designs subject to non-ignorable missing data.
In common with most forms of designed experiment, crossover trials can be affected by missing data. Attempts to devise designs that can mitigate the possible effects of missing data, such as loss of efficiency, or even inestimability of certain contrasts, have been proposed. However, a potentially serious effect of missing data that has not been addressed in designs hitherto is that the treatme...
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In crossover design experiments, the proportional model, where the carryover effects are proportional to their direct treatment effects, has draw attentions in recent years. We discover that the universally optimal design under the traditional model is E-optimal design under the proportional model. Moreover, we establish equivalence theorems of Kiefer-Wolfowitz’s type for four popular optimalit...
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Hedayat and Yang earlier proved that balanced uniform designs in the entire class of crossover designs based on t treatments, n subjects, and pD t periods are universally optimal when n· t .t ¡ 1/=2. Surprisingly, in the class of crossover designs with t treatments and p D t periods, a balanced uniform design may not be universally optimal if the number of subjects exceeds t .t ¡ 1/=2. This art...
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T he case-crossover design has become an accepted method for investigating acute health consequences of transient exposures, or ‘‘triggers’’. This design, originally presented in 1991 by Maclure, can be thought of as a variant of the conventional casecontrol study with individual (pairwise) matching. The principal difference is that a case-crossover study only includes cases, where each serves ...
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Crossover designs in clinical trials are very popular for comparing several non-curative treatments for their eecacy, while having each patient as his/her own control. Many investigators have constructed universally optimal designs for certain repeated measurement experiments. However, most of these statistically optimal designs have certain undesirable features from a clinical perspective. In ...
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ژورنال
عنوان ژورنال: Journal of Modern Applied Statistical Methods
سال: 2012
ISSN: 1538-9472
DOI: 10.22237/jmasm/1335846240